Support cellular energy production, heart health, brain function, and mood with nutrients that optimize methylation.

Methyl-Guard Plus provides superior methyl donors – trimethylglycine, 5-MTHF, and methylcobalamin – combined with bioactive vitamins B2 and B6 in a powerhouse formula for whole-body methylation support.

Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.

Thorne’s Methyl-Guard Plus features betaine (trimethylgycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.

Benefits of Thorne’s Methyl-Guard Plus:

• Enhanced cellular energy production fights fatigue
• Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health
• Promotes fat metabolism and lean body composition
• Promotes liver detoxification of many substances, including hormones like estrogen

Why is methylation important:

Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:

• Cardiovascular health
• Cellular energy production
• Fat metabolism
• DNA production
• Liver detoxification processes

Who can benefit from Thorne's Methyl-Guard Plus:

• Individuals with mutations to MTHFR and other genes that adversely affect methylation
• Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health
• Women seeking support for estrogen metabolism and bone health
• Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition
• Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables

Features of Thorne's Methyl-Guard Plus:

• Betaine, also known as trimethylglycine, is a superior methyl donor 
• The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations
• Active forms of vitamins B2 and B6 – key cofactors in methylation processes
• B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work
• Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard^®

Recommended Use or Purpose: Helps to form red blood cells. Helps to support liver function. Helps support healthy homocysteine levels for the maintenance of cardiovascular health. Methylation support: Methylation - the addition of a methyl group (CH4 - one carbon attached to three hydrogens) to another molecule - is an essential and vital biochemical process within the human body that is involved in a large number of biochemical pathways involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. Recommended Dose (Adults): Take 1 capsule daily or as recommended by your health professional.

See pictures for full ingredient list.